Osawa Takao : Minakata Jin

Tachibana Family

Ay:e Haruka : Tachibana Saki
Koide Keisuke : Tachibana Kyotaro
Aso Yumi : Tachibana Ei

Yoshiwara

Nakatani Miki : Tomonaga Miki / Nokaze
Mizusawa Erena : Hatsune
Takaoka Saki : Yugiri
Musaka Naom:a : Suzuya Hikosaburo
Mizusawa Aki : Hikosaburo's wife

Western Medicine Office

Kiritani Kenta : Saburi Yusuke
Takeda Tetsuya : Ogata Koan
Taguchi Hirom:a : Yamada Junan
Kobay:hi Katsuya : Ito Genboku
Okuda Tatsuhito : Matsumoto Ryojun

Others

Uchino M:aaki : Sakamoto Ryoma
Kohinata Fumiyo : Katsu Rintaro (Kaishuu)
Nakamura Atsuo : Shinmon Tatsugoro
Hirayama Hiroyuki : Chiba Jutaro
Yamamoto Koji : Noguchi Gen

Edo Residents

Toda Naho : Tae
Izawa M:aki : Kiichi
H:himoto Mami : Akane

Guests

Hara Chiaki : Nurse　Hiromi / Town daughter of the Edo era (ep1)
Takubo Issei : Tamada (ep1)
Totsugi Shigeyuki : Dr.Sugita / Express messenger of the Edo era　(ep1)
Matsuo Katsuhisa : palanquin bearer (ep1)
Nakamura Taizo : palanquin bearer (ep1)
Tsuda Kenjiro : hospital doctor (ep1)
Ikeda M:anori : shishi (ep2)
Yoshinaga Shuhei : shishi (ep2)
Nakane Toru : Hikosaburo's doctor (ep4)
Maruoka Shoji : Suzuya patron (ep4)
Shibata Kyoka : young Nokaze (ep4-5)
Kosuda Y:uto : medical office doctor (ep5)
Ruo : medical office doctor (ep5)
Suwabe Hitoshi : danna (ep5)
Tani Momoko : courtesan (ep5)
Shimamura Mika : courtesan (ep5)
H:egawa Kazuki : courtesan (ep5)
Motai Yoko : courtesan (ep5)
Ikenaga Ami : courtesan (ep5)
Ishimaru Kenjiro : Hamaguchi Gihei (Goryo) (ep7-8)
Yoshizawa His:hi : Sawamura Tanosuke (ep8)
Okubo Taka : Chujyoryu doctor (ep8)
Hay:hi Y:ufumi : Kusaka Genzui (ep9-10)
Kawamura Yosuke : Senkichi (ep9-10)
Hamada Manabu : shishi (ep9-10)
Komoto M:ahiro : bushi (ep11)
Nakae Daiki : Yokomatsu